Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719363 | 1.00 | P2RX7 (0.36) | P2RX7S1PR1CXCR3F10F2 | |
| SCHEMBL4723793 | 0.94 | F10 (0.36) | P2RX7CXCR3F10F2ROCK2 | |
| SCHEMBL4723789 | 0.94 | F10 (0.36) | P2RX7CXCR3F10F2ROCK2 | |
| SCHEMBL4719795 | 0.91 | F10 (0.37) | P2RX7S1PR1CXCR3F10F2 | |
| SCHEMBL4719800 | 0.91 | F10 (0.37) | P2RX7S1PR1CXCR3F10F2 | |
| SCHEMBL4721583 | 0.90 | MTNR1A (0.39) | S1PR1CXCR3F10USP2MAPK1 | |
| SCHEMBL4721585 | 0.90 | MTNR1A (0.39) | S1PR1CXCR3F10USP2MAPK1 | |
| SCHEMBL4720196 | 0.90 | TDP1 (0.38) | S1PR1CXCR3F10F2USP2 | |
| SCHEMBL4719462 | 0.90 | CXCR3 (0.35) | S1PR1CXCR3F10USP2LMNA | |
| SCHEMBL4721854 | 0.90 | P2RX7 (0.37) | P2RX7S1PR1CXCR3F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |