Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722372 | 0.93 | F10 (0.38) | MAPTCCR1F2F10CXCR3 | |
| SCHEMBL4719462 | 0.91 | CXCR3 (0.35) | TDP1USP2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4719364 | 0.90 | P2RX7 (0.36) | TDP1USP2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4719363 | 0.90 | P2RX7 (0.36) | TDP1USP2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4724946 | 0.89 | TDP1 (0.39) | TDP1USP2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4721583 | 0.88 | MTNR1A (0.39) | USP2SMN1; SMN2MAPK1KDM4ES1PR1 | |
| SCHEMBL4721585 | 0.88 | MTNR1A (0.39) | USP2SMN1; SMN2MAPK1KDM4ES1PR1 | |
| SCHEMBL14101709 | 0.87 | F10 (0.39) | MAPTS1PR1CCR1F2F10 | |
| SCHEMBL14101712 | 0.87 | F10 (0.39) | MAPTCCR1F2F10CXCR3 | |
| SCHEMBL4724015 | 0.86 | MAPT (0.34) | LMNAMAPTMAPK1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |