Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.48 |
| ▸ | CENPE | Q02224 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718727 | 0.91 | CENPE (0.42) | CENPEMAOBKMT2AALOX5PTGS1 | |
| SCHEMBL4718072 | 0.84 | CENPE (0.46) | CENPEMAOBKMT2AALOX5PTGS1 | |
| SCHEMBL2104779 | 0.83 | GUSB (0.45) | GUSBCENPEMAOBKMT2AL3MBTL1 | |
| SCHEMBL4721237 | 0.80 | SPHK2 (0.44) | CENPEKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL2103273 | 0.79 | CENPE (0.50) | CENPEMAOBKMT2AALOX5PTGS1 | |
| SCHEMBL4718071 | 0.77 | CENPE (0.49) | CENPEKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL4720150 | 0.76 | PTGES (0.46) | CENPEMAOBKMT2AALOX5TSHR | |
| SCHEMBL2103976 | 0.75 | SPHK2 (0.46) | CENPEKMT2A | |
| SCHEMBL2104742 | 0.75 | CENPE (0.46) | CENPEKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL2617475 | 0.75 | HDAC3 (0.51) | GUSBCENPEMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951719-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007056469-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |