Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723157 | 0.94 | F10 (0.32) | MAPTCXCR3LGALS3 | |
| SCHEMBL4719462 | 0.92 | CXCR3 (0.35) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4766343 | 0.91 | F10 (0.31) | CXCR3CYP2C9 | |
| SCHEMBL4722697 | 0.91 | CYP3A4 (0.35) | LMNAMAPTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL4719800 | 0.90 | F10 (0.37) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4719795 | 0.90 | F10 (0.37) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4724909 | 0.89 | PDE4A (0.32) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4723936 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4720845 | 0.88 | PDE4A (0.36) | CXCR3LGALS3KCNK3PDE4APDE4B | |
| SCHEMBL4721664 | 0.87 | F10 (0.35) | MAPTCXCR3LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |