Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721394 | 0.94 | F10 (0.33) | CXCR3F10RBP4 | |
| SCHEMBL4719462 | 0.90 | CXCR3 (0.35) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4724946 | 0.90 | TDP1 (0.39) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4721854 | 0.89 | P2RX7 (0.37) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4721851 | 0.89 | P2RX7 (0.37) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4719683 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2USP2LMNAGAAMAPT | |
| SCHEMBL4722298 | 0.88 | PDE4A (0.35) | MAPTCXCR3KCNK3RBP4 | |
| SCHEMBL4720406 | 0.87 | RBP4 (0.32) | CXCR3TP53RBP4 | |
| SCHEMBL4721648 | 0.86 | MTNR1A (0.39) | SMN1; SMN2USP2MAPK1S1PR1ALDH1A1 | |
| SCHEMBL4721652 | 0.86 | MTNR1A (0.39) | SMN1; SMN2USP2MAPK1S1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |