Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723157 | 0.96 | F10 (0.32) | F10F2CXCR3 | |
| SCHEMBL4724909 | 0.91 | PDE4A (0.32) | F10F2 | |
| SCHEMBL4719683 | 0.91 | SMN1; SMN2 (0.34) | CXCR3CYP2C9 | |
| SCHEMBL4721664 | 0.89 | F10 (0.35) | F10F2CXCR3 | |
| SCHEMBL4721921 | 0.88 | CXCR3 (0.33) | F10F2CXCR3 | |
| SCHEMBL4720845 | 0.87 | PDE4A (0.36) | CXCR3 | |
| SCHEMBL4723688 | 0.87 | S1PR1 (0.35) | F10F2CXCR3 | |
| SCHEMBL4724288 | 0.87 | F10 (0.40) | F10F2CYP3A4CYP2C9NPSR1 | |
| SCHEMBL4724293 | 0.86 | F10 (0.38) | F10F2 | |
| SCHEMBL4721689 | 0.86 | F10 (0.38) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |