SCHEMBL472017

SCHEMBL472017

CC1(C(=O)OC(F)(F)CF)CC2C=CC1C2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.34
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
CETP P11597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203304 0.85 P2RX7 (0.36) P2RX7CYP2D6CYP2C19CETP
SCHEMBL1451420 0.81 P2RX7 (0.37) P2RX7CYP2D6CYP2C19CETP
SCHEMBL472018 0.79 P2RX7 (0.34) P2RX7CYP2D6CYP2C19CETP
SCHEMBL2681014 0.78 P2RX7 (0.33) P2RX7
SCHEMBL5347778 0.78 CYP2D6 (0.35) P2RX7CYP2D6CYP2C19CETP
SCHEMBL32688539 0.77 P2RX7 (0.33) P2RX7CYP2D6CYP2C19CETP
SCHEMBL200115 0.76 P2RX7 (0.41) P2RX7CYP2D6CYP2C19CETP
SCHEMBL18938394 0.76 P2RX7 (0.41) P2RX7CYP2D6CYP2C19CETP
SCHEMBL200228 0.75 CYP2C19 (0.40) P2RX7CYP2D6CYP2C19CETP
SCHEMBL5347783 0.74 P2RX7 (0.35) P2RX7CYP2D6CYP2C19CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412732-B1 Method for preparing cyclic olefin addition polymer of high gas permeability SHINETSU CHEMICAL CO (JP) 2015-08-26 EP disclosed
US-8999043-B2 Air conditioning system DENSO CORPORATION (JP) 2015-04-07 US disclosed
US-20140165838-A1 AIR CONDITIONING SYSTEM DENSO CORPORATION (JP) 2014-06-19 US disclosed
US-8158732-B2 Method for preparing cyclic olefin addition polymer of high gas permeability SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-17 US disclosed
US-20120029158-A1 METHOD FOR PREPARING CYCLIC OLEFIN ADDITION POLYMER OF HIGH GAS PERMEABILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2412732-A1 Method for preparing cyclic olefin addition polymer of high gas permeability Shin-Etsu Chemical Co., Ltd. (JP) 2012-02-01 EP disclosed
EP-2213691-A1 Cycloolefin addition polymer and making method Shin-Etsu Chemical Co., Ltd. (JP) 2010-08-04 EP disclosed
US-20100190950-A1 CYCLOOLEFIN ADDITION POLYMER AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-07-29 US disclosed
US-7049220-B2 Method of forming cavity between multilayered wirings JSR CORPORATION (JP) 2006-05-23 US disclosed
US-7015293-B2 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2006-03-21 US disclosed
US-20050171310-A1 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2005-08-04 US disclosed
EP-1538169-A1 CYCLOOLEFIN ADDITION COPOLYMER AND OPTICAL TRANSPARENT MATERIAL JSR Corporation (JP) 2005-06-08 EP disclosed
US-6790914-B2 TRANSPARENT (CROSSLINKED) RESIN FILM CAN BE USED AS A POLARIZING FILM, SURFACE PROTECTIVE FILM, RETARDATION FILM, TRANSPARENT CONDUCTIVE FILM, LIGHT DIFFUSION FILM, FILM FOR AN EL DISPLAY DEVICE, TRANSPARENT CONDUCTIVE COMPOSITE MATERIAL, JSR CORPORATION (JP) 2004-09-14 US disclosed
US-20040132243-A1 Method of forming cavity between multilayered wirings JSR CORPORATION (JP) 2004-07-08 US disclosed
US-20040106740-A1 Resin film and applications thereof JSR CORPORATION (JP) 2004-06-03 US disclosed
EP-1416528-A2 Method of forming cavity between multilayered wirings JSR Corporation (JP) 2004-05-06 EP disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed