Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628886 | 1.00 | POLB (0.34) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4627985 | 0.83 | POLB (0.39) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3316195 | 0.79 | POLB (0.36) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL1206077 | 0.79 | POLB (0.36) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4718582 | 0.77 | TP53 (0.34) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4629748 | 0.77 | POLB (0.37) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4719694 | 0.77 | POLB (0.37) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4717097 | 0.76 | ACHE (0.46) | ALDH1A1 | |
| SCHEMBL1461712 | 0.69 | ALDH1A1 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL13361364 | 0.69 | GABRP (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1558600-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004037810-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-06 | — | — | WO | disclosed |