Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.33 |
| ▸ | CYP21A2 | P08686 | 6/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721138 | 0.91 | JAK2 (0.34) | SMOMAPTMEN1LMNAKMT2A | |
| SCHEMBL4722717 | 0.90 | MAPT (0.42) | MAPTMEN1LMNAKMT2AHTT | |
| SCHEMBL4722942 | 0.88 | MEN1 (0.31) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL4719872 | 0.87 | SLC40A1 (0.33) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL4719871 | 0.87 | SLC40A1 (0.33) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL4722421 | 0.87 | SLC40A1 (0.33) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL4724241 | 0.85 | F10 (0.35) | MEN1KMT2A | |
| SCHEMBL4719881 | 0.84 | F10 (0.38) | — | |
| SCHEMBL4722289 | 0.84 | IMPDH2 (0.36) | — | |
| SCHEMBL4719259 | 0.83 | L3MBTL1 (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |