Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719881 | 0.91 | F10 (0.38) | F10GAA | |
| SCHEMBL4722942 | 0.88 | MEN1 (0.31) | KMT2AGAAMEN1JAK2JAK1 | |
| SCHEMBL4722896 | 0.88 | TRPV1 (0.32) | — | |
| SCHEMBL4721138 | 0.87 | JAK2 (0.34) | KMT2AALDH1A1MEN1JAK2JAK1 | |
| SCHEMBL4722717 | 0.87 | MAPT (0.42) | KMT2AALDH1A1MEN1JAK2JAK1 | |
| SCHEMBL4720565 | 0.85 | ENPP2 (0.37) | KMT2AMEN1 | |
| SCHEMBL4719259 | 0.84 | L3MBTL1 (0.33) | JAK2JAK1TYK2 | |
| SCHEMBL4722421 | 0.84 | SLC40A1 (0.33) | KMT2AMEN1 | |
| SCHEMBL4719872 | 0.84 | SLC40A1 (0.33) | KMT2AMEN1 | |
| SCHEMBL4719871 | 0.84 | SLC40A1 (0.33) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |