Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 3/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724145 | 0.89 | F10 (0.32) | ALPLALPIGRM7CNR1CNR2 | |
| SCHEMBL14101834 | 0.86 | F2 (0.36) | ALPLALPI | |
| SCHEMBL14101833 | 0.86 | — | — | |
| SCHEMBL4722328 | 0.85 | MEN1 (0.33) | — | |
| SCHEMBL4718937 | 0.80 | P2RX7 (0.38) | — | |
| SCHEMBL4718933 | 0.80 | P2RX7 (0.38) | — | |
| SCHEMBL4719190 | 0.76 | PDE4A (0.40) | EGFRXDHALPLALPIGRM7 | |
| SCHEMBL4723154 | 0.76 | AKR1B10 (0.32) | — | |
| SCHEMBL4721608 | 0.73 | AKR1B10 (0.33) | ALPLALPI | |
| SCHEMBL4722849 | 0.71 | BRD4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |