Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102030 | 0.84 | AR (0.37) | BRD4BRD9BTKGABBR2BRD2 | |
| SCHEMBL4719827 | 0.80 | BRD4 (0.40) | BRD4 | |
| SCHEMBL4724926 | 0.80 | PDE7A (0.37) | BRD4BRD9 | |
| SCHEMBL4724930 | 0.80 | PDE7A (0.37) | BRD4BRD9 | |
| SCHEMBL4723154 | 0.77 | AKR1B10 (0.32) | — | |
| SCHEMBL4719016 | 0.77 | AKR1B10 (0.33) | — | |
| SCHEMBL31589737 | 0.73 | BRD4 (0.64) | BRD4BRD9EP300PBRM1CREBBP | |
| SCHEMBL4720890 | 0.71 | EGFR (0.33) | — | |
| SCHEMBL4720875 | 0.70 | BRD4 (0.37) | BRD4 | |
| SCHEMBL4721608 | 0.67 | AKR1B10 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |