Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721609 | 0.93 | PTK2 (0.33) | NAMPTPTK2IMPDH2MMP1MMP9 | |
| SCHEMBL14102007 | 0.93 | IMPDH2 (0.33) | NAMPTPTK2IMPDH2NTRK1 | |
| SCHEMBL4721371 | 0.89 | PTK2 (0.33) | NAMPTPTK2IMPDH2 | |
| SCHEMBL4722289 | 0.87 | IMPDH2 (0.36) | NAMPTPTK2IMPDH2 | |
| SCHEMBL4719259 | 0.82 | L3MBTL1 (0.33) | IMPDH2 | |
| SCHEMBL4722506 | 0.81 | RIOK2 (0.34) | — | |
| SCHEMBL4720352 | 0.81 | NAMPT (0.30) | NAMPT | |
| SCHEMBL4724113 | 0.81 | MAPT (0.37) | NAMPTPTK2IMPDH2 | |
| SCHEMBL4720084 | 0.80 | NAMPT (0.33) | NAMPTPTK2IMPDH2NTRK1 | |
| SCHEMBL4722805 | 0.79 | MAPT (0.40) | NAMPTMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |