Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722805 | 0.88 | MAPT (0.40) | NAMPTALDH1A1LMNAPOLBMAPT | |
| SCHEMBL4723141 | 0.86 | MAPT (0.39) | NAMPTPTK2IMPDH2ALDH1A1LMNA | |
| SCHEMBL4722197 | 0.86 | MEN1 (0.32) | TRPV1TACR1 | |
| SCHEMBL4719909 | 0.86 | TRPV1 (0.35) | TRPV1ALDH1A1LMNAPOLBTACR1 | |
| SCHEMBL4723705 | 0.82 | TRPV1 (0.30) | TRPV1 | |
| SCHEMBL4721659 | 0.81 | RIOK2 (0.35) | — | |
| SCHEMBL4723349 | 0.81 | PTK2 (0.30) | PTK2 | |
| SCHEMBL4724221 | 0.81 | NTRK1 (0.33) | NTRK1PTK2IMPDH2IMPDH1QPCT | |
| SCHEMBL14102007 | 0.81 | IMPDH2 (0.33) | NAMPTNTRK1PTK2IMPDH2 | |
| SCHEMBL4722896 | 0.80 | TRPV1 (0.32) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |