Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601138 | 0.80 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL4722121 | 0.78 | TSHR (0.30) | TSHRTDP1 | |
| SCHEMBL9400179 | 0.78 | CHRM2 (0.33) | CHRM1TSHRALDH1A1TDP1 | |
| SCHEMBL16403157 | 0.76 | POLB (0.31) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL28609965 | 0.76 | RIPK1 (0.37) | RIPK1FFAR3HMGCRCHRM1TBXA2R | |
| SCHEMBL6264890 | 0.76 | TSHR (0.32) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL3926619 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL8103927 | 0.74 | RIPK1 (0.32) | RIPK1FFAR3ALDH1A1 | |
| SCHEMBL8853478 | 0.72 | MMP8 (0.32) | CYP2D6CYP2C19 | |
| SCHEMBL497097 | 0.69 | TSHR (0.39) | FFAR3HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751920-A | Antitumor compounds | 法马马有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114736219-A | Antitumor compounds | 法马马有限公司 | 2022-07-12 | — | — | CN | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |