Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | LIPC | P11150 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722284 | 1.00 | LIPG (0.38) | LIPGACACBLIPCTTRNOTUM | |
| SCHEMBL4719251 | 0.87 | ACVR1 (0.35) | F10RBP4 | |
| SCHEMBL4722861 | 0.86 | LIPG (0.37) | LIPGACACBLIPCTTRNOTUM | |
| SCHEMBL4722867 | 0.86 | LIPG (0.37) | LIPGACACBLIPCTTRNOTUM | |
| SCHEMBL4722072 | 0.81 | LIPG (0.37) | LIPGACACBLIPCNOTUM | |
| SCHEMBL4722078 | 0.81 | LIPG (0.37) | LIPGACACBLIPCNOTUM | |
| SCHEMBL14101950 | 0.81 | UCHL1 (0.37) | F10RBP4 | |
| SCHEMBL4721277 | 0.80 | LIPG (0.39) | LIPGACACBLIPCTTRNOTUM | |
| SCHEMBL4719937 | 0.80 | ACVR1 (0.32) | — | |
| SCHEMBL4721143 | 0.77 | SUV39H2 (0.36) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |