Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ABL2 | P42684 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722741 | 0.94 | UCHL1 (0.38) | UCHL1USP30S1PR1CXCR3HDAC6 | |
| SCHEMBL4719251 | 0.94 | ACVR1 (0.35) | CXCR3AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4719537 | 0.90 | S1PR1 (0.35) | UCHL1USP30S1PR1CXCR3HDAC6 | |
| SCHEMBL4719937 | 0.86 | ACVR1 (0.32) | CXCR3AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4723936 | 0.85 | SMN1; SMN2 (0.35) | UCHL1USP30S1PR1CXCR3HDAC6 | |
| SCHEMBL4722534 | 0.84 | ACVR1 (0.34) | CXCR3AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4719467 | 0.81 | WDR5 (0.34) | KMT2AACVR1 | |
| SCHEMBL4722281 | 0.81 | LIPG (0.38) | F10RBP4 | |
| SCHEMBL4722284 | 0.81 | LIPG (0.38) | F10RBP4 | |
| SCHEMBL4721394 | 0.80 | F10 (0.33) | CXCR3F10RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |