Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724241 | 0.88 | F10 (0.35) | — | |
| SCHEMBL4719110 | 0.88 | TRPV1 (0.34) | TRPV1 | |
| SCHEMBL4722197 | 0.85 | MEN1 (0.32) | TRPV1 | |
| SCHEMBL4719909 | 0.84 | TRPV1 (0.35) | TRPV1 | |
| SCHEMBL4720512 | 0.84 | SLC40A1 (0.35) | TRPV1RORC | |
| SCHEMBL4720511 | 0.84 | SLC40A1 (0.35) | TRPV1RORC | |
| SCHEMBL4724242 | 0.84 | SLC40A1 (0.35) | TRPV1RORC | |
| SCHEMBL4719078 | 0.83 | PARP1 (0.30) | FFAR1FFAR4GPBAR1 | |
| SCHEMBL4723705 | 0.81 | TRPV1 (0.30) | TRPV1 | |
| SCHEMBL4721659 | 0.80 | RIOK2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |