Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722197 | 0.90 | MEN1 (0.32) | TRPV1MEN1KMT2ATACR1 | |
| SCHEMBL4723705 | 0.86 | TRPV1 (0.30) | TRPV1 | |
| SCHEMBL4721659 | 0.86 | RIOK2 (0.35) | — | |
| SCHEMBL4720084 | 0.86 | NAMPT (0.33) | TRPV1ALDH1A1POLBLMNATACR1 | |
| SCHEMBL4719259 | 0.85 | L3MBTL1 (0.33) | L3MBTL1LMNAPKM | |
| SCHEMBL4719110 | 0.84 | TRPV1 (0.34) | TRPV1MEN1KMT2ALMNA | |
| SCHEMBL4722896 | 0.84 | TRPV1 (0.32) | TRPV1 | |
| SCHEMBL4724242 | 0.83 | SLC40A1 (0.35) | TRPV1P2RX7TACR1METAP2 | |
| SCHEMBL4720511 | 0.83 | SLC40A1 (0.35) | TRPV1P2RX7TACR1METAP2 | |
| SCHEMBL4720512 | 0.83 | SLC40A1 (0.35) | TRPV1P2RX7TACR1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |