SCHEMBL472315

SCHEMBL472315

O=[N+]([O-])c1cc(C=NO)ccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.67
VCAM1 P19320 1/20 0.65
MEN1 O00255 9/20 0.63
KMT2A Q03164 9/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
MAPK1 P28482 2/20 0.63
HSP90AA1 P07900 1/20 0.63
RAB9A P51151 1/20 0.59
ALDH1A1 P00352 5/20 0.58
LMNA P02545 3/20 0.58
NPSR1 Q6W5P4 3/20 0.56
HTT P42858 2/20 0.56
HPGD P15428 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CRHBP P24387 1/20 0.53
CRHR2 Q13324 1/20 0.53
ALOX12 P18054 1/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 2/20 0.53
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472314 1.00 MAPT (0.67) MAPTVCAM1MEN1KMT2AL3MBTL1
SCHEMBL16955615 0.81 VCAM1 (0.71) MAPTVCAM1MEN1KMT2AMAPK1
SCHEMBL3066190 0.80 CRHBP (0.60) MAPTVCAM1MEN1KMT2AL3MBTL1
SCHEMBL472680 0.80 CRHBP (0.60) MAPTVCAM1MEN1KMT2AL3MBTL1
SCHEMBL740207 0.80 MAPT (0.62) MAPTMEN1KMT2AL3MBTL1MAPK1
SCHEMBL472739 0.80 MEN1 (0.62) MAPTMEN1KMT2AL3MBTL1MAPK1
SCHEMBL472679 0.80 CRHBP (0.60) MAPTVCAM1MEN1KMT2AL3MBTL1
SCHEMBL3068948 0.80 MAPT (0.62) MAPTMEN1KMT2AL3MBTL1MAPK1
SCHEMBL472740 0.80 MEN1 (0.62) MAPTMEN1KMT2AL3MBTL1MAPK1
SCHEMBL740884 0.80 MAPT (0.62) MAPTMEN1KMT2AL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102342934-B Animal ectoparasite-controlling agent SUMITOMO CHEMICAL CO 2014-12-24 CN disclosed
US-8785485-B2 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-22 US disclosed
EP-2412240-B1 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
EP-2412239-B1 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL CO (JP) 2014-04-16 EP disclosed
EP-2393777-B1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2013-12-25 EP disclosed
EP-2647285-A2 Pest control composition Sumitomo Chemical Company, Limited (JP) 2013-10-09 EP disclosed
US-8507514-B2 Hydrazide compound and use of the same in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-13 US disclosed
EP-2601836-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company Limited (JP) 2013-06-12 EP disclosed
EP-2601835-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
EP-2601838-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
EP-2412241-A1 Animal ectoparasite-controlling agent Sumitomo Chemical Company, Limited (JP) 2012-02-01 EP disclosed
EP-2393777-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2011-12-14 EP disclosed
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed
EP-2311816-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-20 EP disclosed
EP-2311817-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-20 EP disclosed
EP-2308858-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-13 EP disclosed
WO-2010090344-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-12 WO disclosed
US-20100137372-A1 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
EP-2139874-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2010-01-06 EP disclosed
WO-2008126665-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137372-A1 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL CYP4X1, PRDX5, PRDX1 MAPT 2335/4885VCAM1 4825/4885MEN1 4632/4885
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL H1-4, H1-2, H1-0 MAPT 4590/4885VCAM1 4824/4885MEN1 1591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.