Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068948 | 1.00 | MAPT (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL740884 | 1.00 | MAPT (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL16960708 | 0.81 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL472679 | 0.80 | CRHBP (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL472314 | 0.80 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL472739 | 0.80 | MEN1 (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL472680 | 0.80 | CRHBP (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL472740 | 0.80 | MEN1 (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3066190 | 0.80 | CRHBP (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL472315 | 0.80 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343032-A1 | NOVEL 6-BRIDGED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2014-11-20 | — | — | US | claimed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-21 | — | — | US | disclosed |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-24 | — | — | US | disclosed |
| US-20180318266-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-11-08 | — | — | US | disclosed |
| WO-2018106184-A1 | APPLICATION OF MULTI-KINASE INHIBITOR | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-06-14 | — | — | WO | disclosed |
| EP-2230913-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-18 | — | — | EP | disclosed |
| US-9758530-B2 | 6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection | HOFFMANN-LA ROCHE INC. (US) | 2017-09-12 | — | — | US | disclosed |
| WO-2017135901-A1 | HETEROCYCLIC COMPOUNDS, METHODS OF SYNTHESIS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-08-10 | — | — | WO | disclosed |
| EP-2230913-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| EP-2199287-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20100144808-A1 | SUBSTITUTED ISOXAZOLINE OR ENONE OXIME COMPOUND, AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| EP-2172448-A1 | SUBSTITUTED ISOXAZOLINE OR ENONE OXIME COMPOUND, AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-7662972-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| WO-2009077197-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-06-25 | — | — | WO | disclosed |
| EP-1932836-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND HARMFUL ORGANISM-CONTROLLING AGENT | Nissan Chemical Industries, Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1731512-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | MAPT 1692/4885ALDH1A1 865/4885KDM4E 1334/4885 |
| US-20140343032-A1 | NOVEL 6-BRIDGED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, CYP2D6, TPMT | MAPT 119/4885ALDH1A1 506/4885KDM4E 2710/4885 |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | CHRM3, C3AR1, C9 | MAPT 4809/4885ALDH1A1 3052/4885KDM4E 3243/4885 |
| US-20180318266-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | CHRM3, C3AR1, C9 | MAPT 4809/4885ALDH1A1 3052/4885KDM4E 3243/4885 |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | ATM, CHRM1, NAT1 | MAPT 3594/4885ALDH1A1 806/4885KDM4E 3394/4885 |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | C3AR1, C5, C9 | MAPT 4834/4885ALDH1A1 3404/4885KDM4E 3177/4885 |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | CHRM1, DDT, ATM | MAPT 4210/4885ALDH1A1 1359/4885KDM4E 3630/4885 |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | MAPT 4834/4885ALDH1A1 3404/4885KDM4E 3177/4885 |
| US-20100144808-A1 | SUBSTITUTED ISOXAZOLINE OR ENONE OXIME COMPOUND, AND PEST CONTROL AGENT | MLYCD, MT-CO2, TRHDE | MAPT 3491/4885ALDH1A1 2761/4885KDM4E 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.