SCHEMBL472325

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29742946	1.00	PLAU (0.53)	PLAUHSD17B1HSD17B2ESR1ESR2
	SCHEMBL11963906	0.85	CTDSP1 (0.53)	PLAUHSD17B1HSD17B2ESR1ESR2
	SCHEMBL9098185	0.81	PLAU (0.53)	PLAUHSD17B1HSD17B2ESR1ESR2
	SCHEMBL29592963	0.78	TP53 (0.41)	CYP1A2TRPA1KDM4ETP53TDP1
	SCHEMBL12986970	0.78	TP53 (0.41)	CYP1A2TRPA1KDM4ETP53TDP1
	SCHEMBL16289907	0.78	TP53 (0.41)	CYP1A2TRPA1TP53TDP1MEN1
	SCHEMBL11963905	0.78	NQO2 (0.55)	PLAUHSD17B1HSD17B2CYP1A2KDM4E
	1-Naphthol SCHEMBL8355899	0.78	CYP1A2 (0.61)	PLAUHSD17B1HSD17B2ESR1ESR2
	SCHEMBL17988350	0.78	KDM4E (0.59)	PLAUHSD17B1HSD17B2ESR1ESR2
	SCHEMBL12023085	0.78	MEN1 (0.50)	HSD17B1HSD17B2ESR1ESR2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.