Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994000 | 0.92 | TRPA1 (0.46) | MEN1KMT2AMAPTALOX5ESR1 | |
| SCHEMBL4040346 | 0.90 | MEN1 (0.45) | MEN1KMT2AMAPTALOX5PTPN22 | |
| SCHEMBL7115270 | 0.86 | KMT2A (0.40) | MEN1KMT2AMAPTALOX5PTPN22 | |
| SCHEMBL449311 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2AMAPTCYP1A2HSD17B10 | |
| SCHEMBL27686717 | 0.83 | HPRT1 (0.56) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL12023092 | 0.83 | PLAU (0.45) | MEN1KMT2AESR1ESR2CYP1A2 | |
| SCHEMBL8381351 | 0.78 | PTPN22 (0.60) | MEN1KMT2AMAPTALOX5PTPN22 | |
| SCHEMBL29362162 | 0.78 | PTPN22 (0.65) | MEN1KMT2AMAPTALOX5PTPN22 | |
| SCHEMBL15400598 | 0.78 | PTPN22 (0.65) | MEN1KMT2AMAPTALOX5PTPN22 | |
| SCHEMBL29027 | 0.78 | PTPN22 (0.65) | MEN1KMT2AMAPTALOX5PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9061959-B2 | Method for manufacturing optically active menthol | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| US-9061959-B2 | Method for manufacturing optically active menthol | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| EP-2376411-B1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO PERFUMERY CO LTD (JP) | 2014-11-12 | — | — | EP | disclosed |
| US-8580991-B2 | Aluminium complexes and use thereof as a catalyst in intramolecular ring closure reactions | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-8580991-B2 | Aluminium complexes and use thereof as a catalyst in intramolecular ring closure reactions | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20130253228-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-09-26 | — | — | US | disclosed |
| US-20130253228-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-09-26 | — | — | US | disclosed |
| US-8329931-B2 | Organoaluminum compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-12-11 | — | — | US | disclosed |
| US-8329931-B2 | Organoaluminum compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-12-11 | — | — | US | disclosed |
| US-8329930-B2 | Aluminum complex and use thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-12-11 | — | — | US | disclosed |
| US-8329930-B2 | Aluminum complex and use thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20110295031-A1 | ORGANOALUMINUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-12-01 | — | — | US | disclosed |
| US-20110295031-A1 | ORGANOALUMINUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-12-01 | — | — | US | disclosed |
| US-20110257412-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110257412-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110082308-A1 | ALUMINUM COMPLEX AND USE THEREOF | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-04-07 | — | — | US | disclosed |
| US-20110082308-A1 | ALUMINUM COMPLEX AND USE THEREOF | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-04-07 | — | — | US | disclosed |
| EP-2277623-A2 | Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2011-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257412-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | C9, NFE2L2, ALOX12 | MEN1 378/4885KMT2A 1433/4885MAPT 2933/4885 |
| US-20110295031-A1 | ORGANOALUMINUM COMPOUND | CDC5L, ACSL3, MSMO1 | MEN1 827/4885KMT2A 2669/4885MAPT 3870/4885 |
| US-20130253228-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL | MSMO1, GGPS1, MAN1B1 | MEN1 383/4885KMT2A 4400/4885MAPT 2206/4885 |
| US-20110082308-A1 | ALUMINUM COMPLEX AND USE THEREOF | C9, ALOX12, ALOX5 | MEN1 253/4885KMT2A 1429/4885MAPT 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.