Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719081 | 0.91 | GPR119 (0.48) | GPR119 | |
| SCHEMBL4721156 | 0.89 | GPR119 (0.46) | GPR119 | |
| SCHEMBL4719030 | 0.89 | GPR119 (0.67) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL390003 | 0.88 | GPR119 (0.62) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL4723151 | 0.86 | GPR119 (0.44) | GPR119 | |
| SCHEMBL4718549 | 0.85 | GPR119 (0.46) | GPR119 | |
| SCHEMBL4721934 | 0.84 | GPR119 (0.51) | GPR119 | |
| SCHEMBL4723661 | 0.82 | GPR119 (0.38) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL4718480 | 0.81 | GPR119 (0.44) | GPR119 | |
| SCHEMBL4722419 | 0.81 | GPR119 (0.41) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756084-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2008-11-26 | — | — | EP | claimed |