Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | RORC | P51449 | 15/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721234 | 0.87 | PDE3B (0.46) | PDE3BPDE3ARORCPPARGKMT2A | |
| SCHEMBL4724319 | 0.84 | PDE3B (0.36) | PDE3BPDE3ARORCPPARGKMT2A | |
| SCHEMBL4722184 | 0.82 | PDE3B (0.33) | PDE3BPDE3ARORCPPARGKMT2A | |
| SCHEMBL14102084 | 0.82 | PDE3B (0.34) | PDE3BPDE3ARORCPPARGKMT2A | |
| Hydrochloric Acid SCHEMBL4765559 | 0.81 | PDE3B (0.33) | PDE3BPDE3ARORCPPARGKMT2A | |
| SCHEMBL925047 | 0.78 | PDE3B (0.47) | PDE3BPDE3ARORCKMT2A | |
| SCHEMBL924628 | 0.77 | PDE3B (0.42) | PDE3BPDE3ARORCPPARGKMT2A | |
| SCHEMBL4718971 | 0.76 | CHRM5 (0.33) | PDE3BPDE3ARORCPPARGKMT2A | |
| SCHEMBL4722680 | 0.75 | WDR5 (0.35) | PDE3BPDE3ARORCPPARGKMT2A | |
| SCHEMBL924441 | 0.68 | KDM4E (0.45) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |