Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723904 | 0.84 | PDE3B (0.40) | PDE3BPDE3AKMT2APPARGRORC | |
| SCHEMBL4721234 | 0.80 | PDE3B (0.46) | PDE3BPDE3AKMT2APPARGRORC | |
| SCHEMBL14102084 | 0.80 | PDE3B (0.34) | PDE3BPDE3AKMT2APPARGRORC | |
| SCHEMBL4722184 | 0.80 | PDE3B (0.33) | PDE3BPDE3AKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4765559 | 0.79 | PDE3B (0.33) | PDE3BPDE3AKMT2APPARGRORC | |
| SCHEMBL4718971 | 0.73 | CHRM5 (0.33) | PDE3BPDE3AKMT2APPARGRORC | |
| SCHEMBL4722680 | 0.73 | WDR5 (0.35) | PDE3BPDE3AKMT2APPARGRORC | |
| SCHEMBL30568360 | 0.64 | TRPA1 (0.49) | POLBGAA | |
| SCHEMBL21131387 | 0.64 | TRPA1 (0.49) | POLBGAA | |
| SCHEMBL16438539 | 0.63 | MAPT (0.41) | KMT2APOLBALDH1A1MAPTRBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |