Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725248 | 0.83 | SCARB1 (0.52) | CNR2SCARB1PSEN1PSEN2APH1B | |
| SCHEMBL351636 | 0.83 | FABP4 (0.55) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4727510 | 0.81 | SCARB1 (0.53) | CNR2SCARB1PSEN1PSEN2APH1B | |
| SCHEMBL27998551 | 0.78 | CNR2 (0.51) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2771704 | 0.78 | PLA2G2A (0.65) | PLA2G2A | |
| SCHEMBL350674 | 0.78 | PSEN1 (0.52) | CNR2SCARB1PSEN1PSEN2APH1B | |
| SCHEMBL4160672 | 0.77 | MEN1 (0.56) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4726707 | 0.76 | SCARB1 (0.66) | CNR2SCARB1ALDH1A1HPGDPTGER4 | |
| SCHEMBL4727671 | 0.76 | PLA2G2A (0.54) | PLA2G2A | |
| SCHEMBL5561218 | 0.76 | PLA2G2A (0.75) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |