SCHEMBL350674

SCHEMBL350674

COC(=O)c1cc(OCCCCn2c3ccccc3c3ccccc32)cc(OCCCCn2c3ccccc3c3ccccc32)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 6/20 0.52
PSEN2 P49810 6/20 0.52
APH1B Q8WW43 6/20 0.52
NCSTN Q92542 6/20 0.52
APH1A Q96BI3 6/20 0.52
PSENEN Q9NZ42 6/20 0.52
SCARB1 Q8WTV0 1/20 0.51
HDAC1 Q13547 3/20 0.48
HDAC6 Q9UBN7 3/20 0.48
FABP4 P15090 2/20 0.48
FABP5 Q01469 2/20 0.48
ACHE P22303 1/20 0.48
CNR2 P34972 3/20 0.47
TSHR P16473 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPK1 P28482 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4725248 0.94 SCARB1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4151119 0.93 PSEN1 (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4155967 0.89 MAPT (0.59) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2872778 0.86 PSEN1 (0.43) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL351636 0.86 FABP4 (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2875809 0.85 SCARB1 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL19559314 0.85 MAPT (0.61) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13697269 0.82 MEN1 (0.54) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL10040734 0.82 MEN1 (0.54) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4160672 0.80 MEN1 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160237305-A1 NEW TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES UNIV HOUSTON SYSTEM (US) 2016-08-18 US disclosed
US-20160237305-A1 NEW TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES UNIV HOUSTON SYSTEM (US) 2016-08-18 US disclosed
US-20160237305-A1 NEW TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES UNIV HOUSTON SYSTEM (US) 2016-08-18 US disclosed
US-9248467-B2 Types of electrodeposited polymer coatings with reversible wettability and electro-optical properties ADVINCULA RIGOBERTO (US) 2016-02-02 US disclosed
US-9248467-B2 Types of electrodeposited polymer coatings with reversible wettability and electro-optical properties ADVINCULA RIGOBERTO (US) 2016-02-02 US disclosed
US-9248467-B2 Types of electrodeposited polymer coatings with reversible wettability and electro-optical properties ADVINCULA RIGOBERTO (US) 2016-02-02 US disclosed
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-20120015146-A1 TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-01-19 US disclosed
US-20120015146-A1 TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-01-19 US disclosed
US-20120015146-A1 TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-01-19 US disclosed
WO-2012009238-A2 NEW TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-01-19 WO disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed