SCHEMBL472532

SCHEMBL472532

O=C1NC(=O)C(Br)(Br)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
KDM4E B2RXH2 2/20 0.37
OGT O15294 1/20 0.37
USP2 O75604 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP13 P45452 1/20 0.31
TP53 P04637 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
GABRB3 P28472 1/20 0.30
OPRD1 P41143 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10507443 0.71 LMNA (0.41) LMNAKDM4EOGTUSP2MAPT
SCHEMBL514490 0.67
SCHEMBL2873513 0.66
SCHEMBL4559714 0.64 LMNA (0.41) LMNAKDM4EOGTUSP2MAPT
SCHEMBL1980551 0.64 LMNA (0.41) LMNAKDM4EOGTUSP2MAPT
SCHEMBL137702 0.64 LMNA (0.41) LMNAKDM4EOGTUSP2MAPT
SCHEMBL472442 0.64 LMNA (0.41) LMNAKDM4EOGTUSP2MAPT
SCHEMBL909458 0.63
SCHEMBL4038795 0.63 MMP9 (0.57) LMNAMAPTBLMMMP2MMP9
SCHEMBL8609376 0.62 LMNA (0.39) LMNAKDM4EOGTUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119823062-A Preparation method of pramipexole dihydrochloride related substance BI-II786BS 中国医学科学院药物研究所 2025-04-15 CN claimed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
CN-117050033-A Preparation method of pramipexole dihydrochloride related substances 中国医学科学院药物研究所 2023-11-14 CN claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
CN-104672167-A Preparation method of aminothiazole five-membered heterocyclic compound UNIV ANHUI NORMAL 2015-06-03 CN claimed
US-8962862-B2 Processes for preparing 4-substituted imidazoles CAMBREX KARLSKOGA AB (SE) 2015-02-24 US claimed
WO-2014198241-A1 THIO-1,2,4-TRIAZOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME SUNSHINE LAKE PHARMA CO., LTD. (CN) 2014-12-18 WO claimed
US-20140187789-A1 NEW PROCESSES FOR PREPARING 4-SUBSTITUTED IMIDAZOLES CAMBREX KARLSKOGA AB (SE) 2014-07-03 US claimed
EP-2734508-A1 NEW PROCESSES FOR PREPARING 4-SUBSTITUTED IMIDAZOLES Cambrex Karlskoga Ab (SE) 2014-05-28 EP claimed
CN-103748077-A Novel process for the preparation of 4-substituted imidazoles CAMBREX KARLSKOGA AB 2014-04-23 CN claimed
WO-2013014428-A1 NEW PROCESSES FOR PREPARING 4-SUBSTITUTED IMIDAZOLES CAMBREX KARLSKOGA AB (SE) 2013-01-31 WO claimed
CN-101560206-B Intermediate of pemetrexed disodium, preparation method thereof and method for preparing pemetrexed disodium thereby Suzhou lixin pharmaceutical co ltd 2011-06-22 CN claimed
CN-101560206-A Intermediate of pemetrexed disodium, preparation method thereof and method for preparing pemetrexed disodium thereby SUZHOU LIXIN PHARMACEUTICAL CO (CN) 2009-10-21 CN claimed
EP-1387659-B1 INITIATOR SYSTEM FOR ACID DENTAL FORMULATIONS 3M ESPE AG (DE) 2008-05-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187789-A1 NEW PROCESSES FOR PREPARING 4-SUBSTITUTED IMIDAZOLES CYP4B1, CYP3A4, CYP4F11 LMNA 3233/4885KDM4E 813/4885OGT 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.