SCHEMBL8609376

SCHEMBL8609376

O=C1NC(=O)C(O)(S)C(=O)N1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
OGT O15294 1/20 0.35
USP2 O75604 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
MMP9 P14780 7/20 0.34
MMP2 P08253 6/20 0.34
TP53 P04637 1/20 0.34
MMP8 P22894 5/20 0.34
TDP2 O95551 1/20 0.33
SMAD3 P84022 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137702 0.76 LMNA (0.41) LMNAMAPTKDM4EOGTUSP2
SCHEMBL4686843 0.75
Water SCHEMBL2773218 0.73 LMNA (0.39) LMNAMAPTKDM4EOGTUSP2
SCHEMBL8415310 0.67 LMNA (0.59) LMNAKDM4EMMP9MMP2TP53
SCHEMBL9334278 0.65 LMNA (0.56) LMNAKDM4EMMP9MMP2TP53
SCHEMBL911655 0.65
SCHEMBL2873513 0.64
SCHEMBL11061486 0.63 LMNA (0.55) LMNAMAPTKDM4EOGTUSP2
SCHEMBL10507443 0.62 LMNA (0.41) LMNAMAPTKDM4EOGTUSP2
SCHEMBL9334279 0.62 LMNA (0.46) LMNAKDM4EMMP9MMP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10158114-A None JP disclosed
JP-H10158114-A ADHESIVE FOR DENTISTRY TERUMO CORP 1998-06-16 JP disclosed