SCHEMBL137702

SCHEMBL137702

O=C1NC(=O)C(O)(C2(O)C(=O)NC(=O)NC2=O)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.37
OGT O15294 1/20 0.37
USP2 O75604 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
MMP9 P14780 9/20 0.36
MMP2 P08253 9/20 0.36
TP53 P04637 1/20 0.36
MMP8 P22894 8/20 0.35
TDP2 O95551 1/20 0.34
SMAD3 P84022 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
GABRB3 P28472 1/20 0.30
OPRD1 P41143 1/20 0.30
GABRA2 P47869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4559714 1.00 LMNA (0.41) LMNAMAPTKDM4EOGTUSP2
SCHEMBL8609376 0.76 LMNA (0.39) LMNAMAPTKDM4EOGTUSP2
SCHEMBL8415310 0.69 LMNA (0.59) LMNAKDM4EMMP9MMP2TP53
SCHEMBL11061486 0.65 LMNA (0.55) LMNAMAPTKDM4EOGTUSP2
SCHEMBL472532 0.64 LMNA (0.41) LMNAMAPTKDM4EOGTUSP2
SCHEMBL10507443 0.64 LMNA (0.41) LMNAMAPTKDM4EOGTUSP2
SCHEMBL4875346 0.62 LMNA (0.39) LMNAMAPTKDM4EOGTUSP2
Dimethylbarbiturate SCHEMBL31271990 0.62 LMNA (0.46) LMNAMAPTKDM4EOGTUSP2
SCHEMBL17169741 0.60 LMNA (0.43) LMNAMAPTKDM4EOGTUSP2
SCHEMBL11278121 0.60 LMNA (0.43) LMNAMAPTKDM4EOGTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1069096-B1 Non-azide gas generating composition TRW AIRBAG SYS GMBH (DE) 2005-05-11 EP claimed
EP-1051373-B1 ACID-FREE, GAS-GENERATING COMPOSITION TRW AIRBAG SYS GMBH (DE) 2004-05-26 EP claimed
US-6592778-B2 Method for producing propellant compacts TRW AIRBAG SYSTEMS GMBH & CO. KG (DE) 2003-07-15 US claimed
EP-0949225-B1 Non-azide gas generating composition TRW AIRBAG SYS GMBH & CO KG (DE) 2002-11-20 EP claimed
EP-1006096-B1 Non-azide gas generating composition TRW AIRBAG SYS GMBH & CO KG (DE) 2002-09-25 EP claimed
US-20010018812-A1 Method for producing propellant compacts TRW AIRBAG SYSTEMS GMBH & CO., KG 2001-09-06 US claimed
EP-1130008-A2 Method for producing dense propellent moldings TRW Airbag Systems GmbH & Co. KG (DE) 2001-09-05 EP claimed
EP-1069096-A1 Non-azide gas generating composition TRW Airbag Systems GmbH & Co. KG (DE) 2001-01-17 EP claimed
EP-1051373-A1 ACID-FREE, GAS-GENERATING COMPOSITION TRW Airbag Systems GmbH & Co. KG (DE) 2000-11-15 EP claimed
US-6132537-A Azide-free gas-producing composition TRW AIRBAG SYSTEMS GMBH & CO. KG (DE) 2000-10-17 US claimed
WO-2000032541-A1 ACID-FREE, GAS-GENERATING COMPOSITION TRW AIRBAG SYSTEMS GMBH & CO. KG (DE) 2000-06-08 WO claimed
EP-1006096-A1 Non-azide gas generating composition TRW Airbag Systems GmbH & Co. KG (DE) 2000-06-07 EP claimed
EP-0949225-A1 Non-azide gas generating composition TRW Airbag Systems GmbH & Co. KG (DE) 1999-10-13 EP claimed
US-4112044-A CATALYTIC ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1978-09-05 US claimed
US-4049769-A Separation of uranium isotopes by accelerated isotope exchange reactions ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1977-09-20 US claimed
US-12552882-B2 Polymeric disinfectants and uses thereof TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2026-02-17 US disclosed
EP-4237493-B1 POLYMERIC DISINFECTANTS AND USES THEREOF TECHNION RES & DEV FOUNDATION (IL) 2025-12-10 EP disclosed
US-3961096-A ANIMAL FEEDS THE BOEING COMPANY (US) 1976-06-01 US disclosed
US-3725557-A ALLOXANTIN COMPOUNDS AS ANTIBACTERIAL AND ANTIFUNGAL AGENTS GATES RUBBER CO 1973-04-03 US disclosed
US-3725557-A ALLOXANTIN COMPOUNDS AS ANTIBACTERIAL AND ANTIFUNGAL AGENTS GATES RUBBER CO 1973-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552882-B2 Polymeric disinfectants and uses thereof PIK3C3, POLR1C, CUTA LMNA 1831/4885MAPT 4851/4885KDM4E 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.