SCHEMBL472568

SCHEMBL472568

COC(=O)c1c([Na])c(S(=O)(=O)O)c(-c2ccc3ccccc3c2)c(C(=O)OC)c1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 10/20 0.46
SLC6A4 P31645 6/20 0.46
SLC6A2 P23975 4/20 0.46
ALPL P05186 1/20 0.42
PLAU P00749 3/20 0.41
CYP1A2 P05177 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
SOS1 Q07889 1/20 0.37
HIF1A Q16665 1/20 0.37
POLB P06746 1/20 0.37
HSP90AA1 P07900 1/20 0.36
PAX8 Q06710 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6256131 0.85 LMNA (0.47) ALDH1A1HPGDTSHRMEN1LMNA
SCHEMBL4608806 0.80 SLC6A3 (0.51) SLC6A3SLC6A4SLC6A2ALPLPLAU
SCHEMBL4739089 0.76 LMNA (0.48) ALDH1A1HPGDTSHRMEN1LMNA
SCHEMBL11694263 0.75 SLC6A3 (0.53) SLC6A3SLC6A4SLC6A2ALPLPLAU
SCHEMBL4740265 0.75 LMNA (0.47) ALDH1A1HPGDTSHRMEN1LMNA
SCHEMBL472647 0.75 LMNA (0.47) ALDH1A1HPGDTSHRMEN1LMNA
SCHEMBL11694270 0.72 SLC6A3 (0.56) SLC6A3SLC6A4SLC6A2ALPLPLAU
SCHEMBL269273 0.70 SLC6A3 (0.60) SLC6A3SLC6A4SLC6A2ALPLPLAU
SCHEMBL4736926 0.70 LMNA (0.44) CYP1A2ALDH1A1HPGDCYP2C9TSHR
SCHEMBL6469625 0.69 LMNA (0.69) SLC6A3SLC6A4SLC6A2ALPLCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364331-B1 Water-dissipatable polyester resins and coatings prepared therefrom EASTMAN KODAK CO (US) 1994-06-08 EP claimed
US-4990593-A Curable with amino resin; waterproof enamel; polyesteramides from aminocarboxylic acids, amino alcohols, sulfonated acids, glycols, diamines EASTMAN KODAK COMPANY (US) 1991-02-05 US claimed
EP-0409916-A1 WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM EASTMAN KODAK COMPANY (US) 1991-01-30 EP claimed
WO-1990003994-A2 WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM EASTMAN KODAK COMPANY (US) 1990-04-19 WO claimed
EP-0364331-A2 Water-dissipatable polyester resins and coatings prepared therefrom EASTMAN CHEMICAL COMPANY (US) 1990-04-18 EP claimed
US-4910292-A Having carbonyloxy linking groups EASTMAN KODAK COMPANY (US) 1990-03-20 US claimed
EP-2412423-B1 Acetoacetate polymer coated aldehyde removal filter EASTMAN CHEM CO (US) 2016-12-14 EP disclosed
EP-2099323-B1 ACETOACETATE POLYMER COATED ALDEHYDE REMOVAL FILTER EASTMAN CHEM CO (US) 2015-05-27 EP disclosed
EP-2412422-A1 Acetoacetate polymer coated aldehyde renoval filter Eastman Chemical Company (US) 2012-02-01 EP disclosed
EP-2412423-A1 Acetoacatate polymer coated aldehyde removal filter Eastman Chemical Company (US) 2012-02-01 EP disclosed
US-7855261-B2 Aldehyde removal EASTMAN CHEMICAL COMPANY (US) 2010-12-21 US disclosed
EP-2099323-A2 ACETOACETATE POLYMER COATED ALDEHYDE REMOVAL FILTER Eastman Chemical Company (US) 2009-09-16 EP disclosed
WO-2008085852-A1 USE OF COPOLYMERIZABLE SULFONATE SALTS TO PROMOTE CHAR FORMATION IN POLYESTERS AND COPOLYESTERS EASTMAN CHEMICAL COMPANY (US) 2008-07-17 WO disclosed
EP-0364331-A2 Water-dissipatable polyester resins and coatings prepared therefrom EASTMAN CHEMICAL COMPANY (US) 1990-04-18 EP disclosed
US-4910292-A Having carbonyloxy linking groups EASTMAN KODAK COMPANY (US) 1990-03-20 US disclosed
EP-0033783-B1 POLYESTER ADHESIVES National Starch and Chemical Corporation (US) 1982-12-22 EP disclosed
US-4300580-A Hair grooming method using linear polyesters EASTMAN KODAK COMPANY (US) 1981-11-17 US disclosed
EP-0033783-A2 Polyester adhesives National Starch and Chemical Corporation (US) 1981-08-19 EP disclosed
US-4257928-A COMPRISING DIBENZALSORBITOL AND A POLYESTER CONTAINING SULFONATE GROUPS PERMABOND INTERNATIONAL CORPORATION (US) 1981-03-24 US disclosed
US-4119680-A SULFONATE MONOMER, UNSATURATED DICARBOXYLIC ACIDS EASTMAN KODAK COMPANY (US) 1978-10-10 US disclosed