Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740265 | 0.90 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL6256131 | 0.90 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL472647 | 0.90 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL472552 | 0.79 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL4739070 | 0.76 | ALDH1A1 (0.52) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL472568 | 0.76 | SLC6A3 (0.46) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4739961 | 0.75 | CA1 (0.39) | LMNAALDH1A1TP53HTTMEN1 | |
| SCHEMBL4736926 | 0.74 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL11227892 | 0.72 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL4739083 | 0.72 | CNR2 (0.46) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085852-A1 | USE OF COPOLYMERIZABLE SULFONATE SALTS TO PROMOTE CHAR FORMATION IN POLYESTERS AND COPOLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 2008-07-17 | — | — | WO | disclosed |
| US-20080167440-A1 | Use of copolymerizable sulfonate salts to promote char formation in polyesters and copolyesters | EASTMAN CHEMICAL COMPANY | 2008-07-10 | — | — | US | disclosed |