Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608806 | 0.86 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2ALDH1A1HPGD | |
| SCHEMBL11694270 | 0.80 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2ALDH1A1HPGD | |
| SCHEMBL751983 | 0.80 | CYP2D6 (0.52) | ALDH1A1HPGDKDM4ECYP1A2HSD17B10 | |
| SCHEMBL11699326 | 0.78 | ALDH1A1 (0.47) | SLC6A3SLC6A4SLC6A2ALDH1A1HPGD | |
| SCHEMBL16384877 | 0.75 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2ALDH1A1HPGD | |
| SCHEMBL472568 | 0.75 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2ALDH1A1HPGD | |
| SCHEMBL29002787 | 0.73 | GPR84 (0.47) | ALDH1A1HPGDCYP1A2HSD17B10MEN1 | |
| SCHEMBL3679271 | 0.73 | ALDH1A1 (0.51) | SLC6A3SLC6A4SLC6A2ALDH1A1HPGD | |
| SCHEMBL4741185 | 0.72 | MAPT (0.41) | ALDH1A1HPGDKDM4ENPSR1CYP1A2 | |
| SCHEMBL13152864 | 0.71 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052368-A | WATER-DISPELLABLE HOT MELT POLYESTER ADHESIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-10-04 | — | — | US | disclosed |