Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.41 |
| ▸ | BRAF | P15056 | 15/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728383 | 0.79 | NPC1 (0.52) | RAF1BRAFADORA2A | |
| SCHEMBL4779686 | 0.78 | RAF1 (0.41) | RAF1BRAFADORA2A | |
| SCHEMBL4729210 | 0.78 | TRPV1 (0.42) | RAF1BRAFADORA2A | |
| SCHEMBL4729212 | 0.77 | TRPV1 (0.41) | RAF1BRAFADORA2A | |
| SCHEMBL4729484 | 0.77 | TRPV1 (0.41) | RAF1BRAFADORA2A | |
| SCHEMBL4779963 | 0.77 | BRAF (0.46) | RAF1BRAF | |
| SCHEMBL4729375 | 0.77 | MAPK14 (0.61) | RAF1BRAF | |
| SCHEMBL4782204 | 0.76 | RAF1 (0.69) | RAF1BRAF | |
| SCHEMBL14293723 | 0.76 | MAPK14 (0.42) | RAF1BRAF | |
| SCHEMBL4726226 | 0.76 | RAF1 (0.46) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |