SCHEMBL472592

SCHEMBL472592

O=c1c2ccccc2[s+]([O-])c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
GLA P06280 3/20 0.41
KDM4E B2RXH2 3/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HTT P42858 2/20 0.41
GAA P10253 1/20 0.41
ATM Q13315 1/20 0.41
CYP3A4 P08684 1/20 0.41
PGAM1 P18669 1/20 0.41
MAOA P21397 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
P2RX4 Q99571 2/20 0.36
MAPK1 P28482 1/20 0.33
POLB P06746 2/20 0.32
TTR P02766 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9477914 0.84 AKR1B1 (0.34) ALDH1A1GLAKDM4ELMNAMAPT
SCHEMBL205562 0.84 CYP2A6 (0.33) ALDH1A1HSD17B10
SCHEMBL30286606 0.84 CYP2A6 (0.33) ALDH1A1HSD17B10
SCHEMBL4634507 0.83 KDM4E (0.47) ALDH1A1KDM4ELMNAHPGDHTT
SCHEMBL29902867 0.79 TNKS (0.38) ALDH1A1KDM4EMAPTHPGDSMN1; SMN2
SCHEMBL6130719 0.79 ABCG2 (0.41) ALDH1A1KDM4EMAPTHPGDATM
SCHEMBL3811372 0.75 IKBKE (0.36) KDM4ELMNAMAPTHPGDSMN1; SMN2
SCHEMBL12269543 0.75 ALDH1A1 (0.41) ALDH1A1GLAKDM4ELMNAMAPT
SCHEMBL13326153 0.73 ALDH1A1 (0.39) ALDH1A1GLAKDM4ELMNAMAPT
SCHEMBL3142984 0.73 ALDH1A1 (0.39) ALDH1A1GLAKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367745-B2 Includes alkaline earth metal oxide as acidity neutralization stabilizer; quick setting, mechanical strength; repairing prosthesis GC CORPORATION (JP) 2013-02-05 US claimed
US-7678843-B2 Dental restorative material composition GC CORPORATION (JP) 2010-03-16 US claimed
US-5770638-A CONSISTS OF TETRAHYDROFURFURYL METHACRYLATE, ONE OR MORE METHACRYLATE HAVING ATLEAST ONE DOUBLE BOND SELECTED FROM DI-2-METHACRYLOXYETHYL-2,2-4-TRIMETHYLHEXAMETHYLENE DICARBAMATE AND OTHER ACRYLATED CARBAMATE AND PHOTOINITIATORS GC CORPORATION (JP) 1998-06-23 US claimed
JP-58120605-A None JP disclosed
JP-10212286-A None JP disclosed
JP-10182634-A None JP disclosed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition GC CORPORATION (JP) 2026-04-14 US disclosed
EP-3669854-B1 PHOTOPOLYMERIZABLE DENTAL COMPOSITION G C DENTAL IND CORP (JP) 2026-04-08 EP disclosed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-4544467-A PHOSPHOROUS-CONTAINING UNSATURATED MONOMER , SULFUR COMPOUND AND PHOTOINITIATOR; BONDING STRENGTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-01 US disclosed
EP-0132318-A1 Light-curable dentin and enamel adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-30 EP disclosed
JP-S58120605-A CURING OF PHOTOPOLYMERIZABLE RESIN COMPOSITION USING THIOXANTHONE SULFOXIDE OR THIOXANTHONE SULFODIOXIDE DERIVATIVE NIPPON KAYAKU CO LTD 1983-07-18 JP disclosed
US-4259494-A ANTIHISTAMINIC, ANTITUSSIVE, ANTIINFLAMMATORY, SEDATIVE, DIURETIC WARNER-LAMBERT COMPANY (US) 1981-03-31 US disclosed
US-4110448-A ANTIHISTAMINE, ANTITUSSIVE, ANTIINFLAMMATORY, SEDATIVE, DIURETIC WARNER-LAMBERT COMPANY (US) 1978-08-29 US disclosed
US-4076723-A ANTIHISTAMINES, ANTITUSSIVE AGENTS, ANTIINFLAMMATORY AGENTS, SEDATIVES, DIURETICS WARNER-LAMBERT COMPANY (US) 1978-02-28 US disclosed
US-4033981-A ANTIHISTOMINIC, ANTIINFLAMMATORY, SEDATIVES, DIURETICS WARNER-LAMBERT COMPANY (US) 1977-07-05 US disclosed
US-3992376-A ANTIHISTAMINES, ANTITUSSIVES, SEDATIVES, ANTIINFLAMMATORY AGENTS AND DIURETICS WARNER-LAMBERT COMPANY (US) 1976-11-16 US disclosed
US-3978052-A ANTIHISTAMINIC, ANTITUSSIVE, ANTIINFLAMMATORY, DIURETIC WARNER-LAMBERT COMPANY (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition SARS1, SPIN1, ESPL1 ALDH1A1 3420/4885GLA 4142/4885KDM4E 1434/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 ALDH1A1 93/4885GLA 1026/4885KDM4E 1053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.