Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23727751 | 0.84 | HPGD (0.61) | L3MBTL1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL1425543 | 0.84 | HPGD (0.66) | L3MBTL1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL2929978 | 0.83 | L3MBTL1 (0.71) | L3MBTL1USP2SMN1; SMN2TSHRHPGD | |
| SCHEMBL10077130 | 0.83 | L3MBTL1 (0.71) | L3MBTL1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL7401505 | 0.83 | HPGD (0.69) | L3MBTL1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL12448379 | 0.81 | L3MBTL1 (0.49) | L3MBTL1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL8898560 | 0.81 | POLB (0.55) | L3MBTL1TSHRHPGDALDH1A1KMT2A | |
| SCHEMBL4188852 | 0.80 | LMNA (0.50) | L3MBTL1LMNASMN1; SMN2TSHRHPGD | |
| SCHEMBL8220304 | 0.79 | HPGD (0.46) | L3MBTL1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL8898022 | 0.78 | L3MBTL1 (0.64) | L3MBTL1LMNAUSP2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |