Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425482 | 0.86 | HPGD (0.58) | L3MBTL1ALDH1A1LMNAKCNJ1KCNH2 | |
| SCHEMBL23728205 | 0.86 | HPGD (0.54) | ALDH1A1LMNAKCNJ1KCNH2HPGD | |
| SCHEMBL8897735 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL8896530 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAKCNJ1SMN1; SMN2HTT | |
| SCHEMBL5726074 | 0.78 | ATM (0.63) | L3MBTL1ALDH1A1SIRT6LMNASMN1; SMN2 | |
| SCHEMBL2929978 | 0.78 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL4725945 | 0.78 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL10077130 | 0.78 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1HPGDCYP2C19GAA | |
| SCHEMBL5650248 | 0.76 | HTT (0.46) | ALDH1A1LMNAKCNJ1KCNH2HTT | |
| SCHEMBL4185130 | 0.76 | HTT (0.46) | ALDH1A1LMNAKCNJ1KCNH2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |