Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726095 | 0.85 | PPARG (0.46) | MAOBHIF1AMAOAPPARGKCNE1 | |
| SCHEMBL4784487 | 0.84 | ALDH1A1 (0.40) | MAOBPPARGALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4727314 | 0.81 | LMNA (0.40) | MAOBALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL2171555 | 0.81 | ALDH1A1 (0.45) | ALDH1A1NFKB1L3MBTL1 | |
| SCHEMBL4726886 | 0.79 | TDP2 (0.41) | HIF1AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL4728256 | 0.79 | ALPG (0.41) | MAOBALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL9747861 | 0.79 | MAOB (0.62) | MAOBHIF1AMAOAKCNE1KCNQ1 | |
| SCHEMBL4730667 | 0.77 | CNR2 (0.37) | ALDH1A1LMNAL3MBTL1PPARA | |
| SCHEMBL4730195 | 0.73 | ALPG (0.41) | MAOBALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL2761859 | 0.71 | MAOB (0.67) | MAOBMAOAALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |