Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784489 | 0.85 | CYP1A1 (0.41) | PPARGMAOBALDH1A1L3MBTL1HPGD | |
| SCHEMBL4726092 | 0.85 | MAOB (0.52) | PPARGMAOBALDH1A1NR1H4KCNE1 | |
| SCHEMBL4727318 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL4729580 | 0.80 | CYP11B2 (0.51) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL4728535 | 0.80 | CYP11B2 (0.40) | ALDH1A1KCNE1KCNQ1LMNAL3MBTL1 | |
| SCHEMBL4728259 | 0.80 | CYP11B2 (0.40) | MAOBALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL4730197 | 0.73 | MAPK1 (0.40) | MAOBALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL4726123 | 0.73 | TDP2 (0.41) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL4784487 | 0.68 | ALDH1A1 (0.40) | PPARGMAOBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2171555 | 0.68 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MEN1KMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |