Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873786 | 0.93 | FFAR3 (0.39) | ALDH1A1SMN1; SMN2FFAR3 | |
| SCHEMBL874031 | 0.91 | FFAR3 (0.43) | ALDH1A1FFAR3 | |
| SCHEMBL7739592 | 0.86 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2FFAR3MEN1CYP3A4 | |
| SCHEMBL12910473 | 0.78 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2FFAR3MEN1CYP3A4 | |
| SCHEMBL8527912 | 0.75 | FFAR3 (0.42) | ALDH1A1SMN1; SMN2FFAR3MEN1CYP3A4 | |
| SCHEMBL14445398 | 0.75 | NPSR1 (0.50) | ALDH1A1SMN1; SMN2FFAR3MEN1CYP3A4 | |
| SCHEMBL17852 | 0.75 | NPSR1 (0.50) | ALDH1A1SMN1; SMN2FFAR3MEN1CYP3A4 | |
| SCHEMBL16609936 | 0.74 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FFAR3P2RX7CETP | |
| SCHEMBL651351 | 0.74 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FFAR3P2RX7CETP | |
| SCHEMBL246831 | 0.74 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FFAR3P2RX7CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |