Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873786 | 0.93 | FFAR3 (0.39) | FFAR3ALDH1A1 | |
| SCHEMBL4726410 | 0.91 | ALDH1A1 (0.40) | FFAR3ALDH1A1 | |
| SCHEMBL7739592 | 0.74 | ALDH1A1 (0.45) | FFAR3ALDH1A1TSHR | |
| SCHEMBL27567348 | 0.72 | — | — | |
| SCHEMBL5798806 | 0.72 | CYP4F2 (0.31) | — | |
| SCHEMBL932523 | 0.71 | — | — | |
| SCHEMBL24780354 | 0.70 | FFAR3 (0.40) | FFAR3TSHR | |
| SCHEMBL383568 | 0.69 | — | — | |
| SCHEMBL283125 | 0.69 | — | — | |
| SCHEMBL9876428 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |