Potassium Ion

Potassium Ion

SCHEMBL472665

O=C([O-])c1cc(C(=O)[O-])cc(S(=O)(=O)O)c1.[K+].[K+]

nearest known ligand 0.61

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.61
FYN P06241 1/20 0.61
TIMP3 P35625 2/20 0.40
LMNA P02545 1/20 0.39
ING2 Q9H160 1/20 0.39
CA2 P00918 6/20 0.38
CA1 P00915 5/20 0.38
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
NT5E P21589 2/20 0.38
HSD17B10 Q99714 3/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
CASP6 P55212 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.35
NSD2 O96028 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL28394777 0.98 LCK (0.59) LCKFYNTIMP3LMNAING2
SCHEMBL258409 0.95 LCK (0.61) LCKFYNTIMP3LMNAING2
SCHEMBL18192037 0.95 LCK (0.61) LCKFYNTIMP3LMNAING2
Lithium Ion SCHEMBL433795 0.95 LCK (0.61) LCKFYNTIMP3LMNAING2
Zinc Ion SCHEMBL15387742 0.95 LCK (0.61) LCKFYNTIMP3LMNAING2
SCHEMBL6850489 0.95 LCK (0.61) LCKFYNTIMP3LMNAING2
SCHEMBL6292956 0.95 LCK (0.61) LCKFYNTIMP3LMNAING2
Lithium Ion SCHEMBL28391984 0.93 LCK (0.59) LCKFYNTIMP3LMNAING2
Potassium Ion SCHEMBL5698373 0.92 LCK (0.77) LCKFYNTIMP3LMNAING2
SCHEMBL7714609 0.91 LCK (0.56) LCKFYNTIMP3LMNAING2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115427481-B Masterbatch formulations based on polyamides 艾德凡斯化学公司 2024-05-31 CN claimed
US-11920009-B2 Polyamide-based masterbatch formulation ADVANSIX RESINS & CHEMICALS LLC (US) 2024-03-05 US claimed
EP-4107207-A1 STAIN-RESISTANT BRANCHED POLYAMIDES AdvanSix Resins & Chemicals LLC (US) 2022-12-28 EP claimed
EP-4107208-A1 POLYAMIDE-BASED MASTERBATCH FORMULATION AdvanSix Resins & Chemicals LLC (US) 2022-12-28 EP claimed
CN-115427481-A Polyamide-based masterbatch formulation 艾德凡斯化学公司 2022-12-02 CN claimed
CN-115103870-A Stain-resistant branched polyamides 艾德凡斯化学公司 2022-09-23 CN claimed
US-20210253803-A1 POLYAMIDE-BASED MASTERBATCH FORMULATION ADVANSIX RESINS & CHEMICALS LLC 2021-08-19 US claimed
US-20210253794-A1 STAIN-RESISTANT BRANCHED POLYAMIDES TRUIST BANK, AS ADMINISTRATIVE AGENT 2021-08-19 US claimed
US-9688823-B2 Aliphatic/semi-aromatic block copolyamide RHODIA OPERATIONS (FR) 2017-06-27 US claimed
US-20160108174-A1 POLYAMIDES COMPRISING ME-BHT, COMPOSITIONS COMPRISING SUCH A POLYAMIDE, SHAPED ARTICLES COMPRISING SUCH A POLYAMIDE OR SUCH A COMPOSITION PERFORMANCE POLYAMIDES, SAS (FR) 2016-04-21 US claimed
WO-2002081544-A1 MODIFIED ALKYD COMPOSITIONS COMPRISING POLYOL LATEX COMPOSITIONS AND PROCESSES OF MAKING THEM EASTMAN CHEMICAL COMPANY (US) 2002-10-17 WO claimed
WO-2002081545-A1 MODIFIED ALKYD COMPOSITIONS COMPRISING DIOL LATEX COMPOSITIONS AND PROCESSES OF MAKING THE SAME EASTMAN CHEMICAL COMPANY (US) 2002-10-17 WO claimed
US-20020147270-A1 Modified alkyd compositions comprising polyol latex compositions and processes of making them EASTMAN CHEMICAL COMPANY 2002-10-10 US claimed
US-5695884-A POLYESTERURETHANE COPOLYMER TOYO BOSEKI KABUSHIKI KAISHA (JP) 1997-12-09 US claimed
US-5378757-A Containing sulfonate groups EASTMAN CHEMICAL COMPANY (US) 1995-01-03 US claimed
US-4990593-A Curable with amino resin; waterproof enamel; polyesteramides from aminocarboxylic acids, amino alcohols, sulfonated acids, glycols, diamines EASTMAN KODAK COMPANY (US) 1991-02-05 US claimed
EP-0409916-A1 WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM EASTMAN KODAK COMPANY (US) 1991-01-30 EP claimed
WO-1990003994-A2 WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM EASTMAN KODAK COMPANY (US) 1990-04-19 WO claimed
EP-0364331-A2 Water-dissipatable polyester resins and coatings prepared therefrom EASTMAN CHEMICAL COMPANY (US) 1990-04-18 EP claimed
US-4910292-A Having carbonyloxy linking groups EASTMAN KODAK COMPANY (US) 1990-03-20 US claimed