Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.66 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728198 | 0.85 | RORC (0.58) | RORCNPY5RCNR2ALDH1A1KDM4E | |
| SCHEMBL4726986 | 0.85 | NPY5R (0.71) | RORCNPY5RCNR2ALDH1A1HPGD | |
| SCHEMBL4726409 | 0.81 | NPY5R (0.62) | RORCNPY5RALDH1A1HPGDKDM4E | |
| SCHEMBL4726208 | 0.79 | CNR2 (0.67) | RORCNPY5RCNR2ALDH1A1HPGD | |
| SCHEMBL29643278 | 0.78 | MEN1 (0.55) | RORCNPY5RALDH1A1HPGDKDM4E | |
| SCHEMBL4726729 | 0.78 | ALDH1A1 (0.68) | RORCNPY5RALDH1A1HPGDKDM4E | |
| SCHEMBL4726929 | 0.78 | KDM4E (0.69) | RORCNPY5RCNR2ALDH1A1HPGD | |
| SCHEMBL4727525 | 0.78 | MEN1 (0.55) | RORCNPY5RALDH1A1HPGDKDM4E | |
| SCHEMBL4728289 | 0.78 | HPGD (0.52) | RORCNPY5RCNR2ALDH1A1HPGD | |
| SCHEMBL4728742 | 0.77 | PTGER4 (0.62) | RORCNPY5RCNR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |