Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | RORC | P51449 | 8/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267709 | 0.80 | ALDH1A1 (0.51) | CNR2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4726986 | 0.80 | NPY5R (0.71) | HPGDRORCNPY5RCNR2MEN1 | |
| SCHEMBL4726848 | 0.80 | KDM4E (0.58) | HPGDCNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL4726977 | 0.78 | RORC (0.66) | HPGDRORCNPY5RCNR2MEN1 | |
| SCHEMBL4726208 | 0.74 | CNR2 (0.67) | HPGDRORCNPY5RCNR2ALDH1A1 | |
| SCHEMBL19248415 | 0.74 | CNR2 (0.67) | RORCCNR2 | |
| SCHEMBL13635205 | 0.73 | ALDH1A1 (0.51) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13011205 | 0.73 | ALDH1A1 (0.51) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13011202 | 0.73 | ALDH1A1 (0.51) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16120098 | 0.72 | ALDH1A1 (0.67) | HPGDRORCNPY5RCNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |