Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926881 | 0.98 | KDM4E (0.56) | CYP3A4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL11038698 | 0.82 | KDM4E (0.53) | CYP3A4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL20414372 | 0.80 | DHODH (0.52) | CYP3A4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL28623461 | 0.80 | ALOX15 (0.54) | CYP3A4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL2532916 | 0.80 | TNKS2 (0.46) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL10630961 | 0.79 | TLR8 (0.59) | CYP3A4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL7262455 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9988793 | 0.78 | DHODH (0.53) | CYP3A4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL7550406 | 0.78 | TLR8 (0.55) | CYP3A4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL7548623 | 0.78 | TLR8 (0.55) | CYP3A4MAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598651-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | Sanofi-Aventis Deutschland GmbH (DE) | 2013-06-05 | — | — | EP | disclosed |
| US-20130123360-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012013621-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| EP-2412819-A1 | Methods and uses relating to the identification of compound associated with bacterial infection | Sanofi-Aventis Deutschland GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |