Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | BID | P55957 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623461 | 0.98 | ALOX15 (0.54) | KDM4EUSP2ALDH1A1GLACYP3A4 | |
| SCHEMBL30744751 | 0.88 | KDM4E (0.59) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL28308942 | 0.86 | PLA2G2A (0.49) | KDM4EUSP2ALDH1A1GLACYP3A4 | |
| SCHEMBL30744791 | 0.84 | ALOX15 (0.61) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| Phthalic Acid SCHEMBL28229283 | 0.83 | DHODH (0.56) | KDM4EUSP2ALDH1A1GLACYP3A4 | |
| SCHEMBL11038406 | 0.82 | BID (0.46) | KDM4EUSP2ALDH1A1GLACYP3A4 | |
| Phthalic Acid SCHEMBL28034650 | 0.82 | DHODH (0.55) | KDM4EUSP2ALDH1A1GLACYP3A4 | |
| SCHEMBL6080305 | 0.82 | BID (0.56) | KDM4EUSP2ALDH1A1GLACYP3A4 | |
| SCHEMBL472714 | 0.82 | CYP3A4 (0.59) | KDM4EUSP2ALDH1A1GLACYP3A4 | |
| SCHEMBL6602488 | 0.81 | TLR8 (0.47) | KDM4EUSP2ALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124577-A1 | NEW CHELATE FORMING QUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HÖGBERG, Sverker (SE) | 1984-11-14 | — | — | EP | disclosed |
| WO-1984001947-A1 | NEW CHELATE FORMING QUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HOEGBERG SVERKER | 1984-05-24 | — | — | WO | disclosed |