Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038698 | 0.98 | KDM4E (0.53) | ALOX15KDM4ETLR8USP2ALDH1A1 | |
| SCHEMBL30744751 | 0.89 | KDM4E (0.59) | ALOX15KDM4EALDH1A1GLAGAA | |
| SCHEMBL28308942 | 0.88 | PLA2G2A (0.49) | ALOX15KDM4ETLR8USP2ALDH1A1 | |
| SCHEMBL30744791 | 0.85 | ALOX15 (0.61) | ALOX15KDM4EALDH1A1HPGDHSD17B10 | |
| Phthalic Acid SCHEMBL28229283 | 0.82 | DHODH (0.56) | KDM4ETLR8USP2ALDH1A1GLA | |
| SCHEMBL22926881 | 0.81 | KDM4E (0.56) | KDM4ETLR8USP2ALDH1A1GLA | |
| SCHEMBL11038406 | 0.81 | BID (0.46) | ALOX15KDM4ETLR8USP2ALDH1A1 | |
| SCHEMBL6080305 | 0.81 | BID (0.56) | ALOX15KDM4EUSP2ALDH1A1GLA | |
| Phthalic Acid SCHEMBL28034650 | 0.81 | DHODH (0.55) | KDM4ETLR8USP2ALDH1A1GLA | |
| SCHEMBL27928660 | 0.80 | ALOX15 (0.58) | ALOX15KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942547-B | Novel quinoline-substituted triazole compound with biological activity and synthesis method and application thereof | 河南师范大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-109942547-A | Biologically active novel quinoline substituted trinitrogen azole compound and its synthetic method and application | 河南师范大学 | 2019-06-28 | — | — | CN | disclosed |