Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.56 |
| ▸ | HTR1A | P08908 | 17/20 | 0.56 |
| ▸ | HTR2A | P28223 | 16/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727335 | 0.84 | DRD2 (0.73) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4728033 | 0.78 | HTR1A (0.71) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4725929 | 0.74 | DRD2 (0.73) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4729269 | 0.72 | DRD2 (1.00) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4729240 | 0.71 | DRD2 (0.75) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4727212 | 0.71 | DRD2 (1.00) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4728872 | 0.70 | DRD2 (0.74) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL5217694 | 0.70 | ADRB1 (0.47) | DRD2HTR1AHTR2A | |
| SCHEMBL5251084 | 0.69 | DRD2 (0.70) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4728059 | 0.69 | DRD2 (0.75) | DRD2HTR1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | claimed |