Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4757267 | 0.91 | GAA (0.37) | CYP2D6POLBLMNACYP1A2HTT | |
| SCHEMBL3679108 | 0.76 | ACACB (0.43) | HTT | |
| SCHEMBL15362472 | 0.76 | GABRA1 (0.60) | GABRA1GABRB2CYP3A4SLC6A2POLB | |
| SCHEMBL535657 | 0.75 | GABRA1 (0.41) | GABRA1GABRB2CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL4419612 | 0.75 | GABRA1 (0.41) | GABRA1GABRB2CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL1741996 | 0.75 | GABRA1 (0.41) | GABRA1GABRB2CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL29688500 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4SLC6A2POLB | |
| SCHEMBL935174 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4SLC6A2POLB | |
| SCHEMBL1579875 | 0.72 | POLB (0.41) | CYP2D6POLBLMNACYP1A2HPGD | |
| SCHEMBL3664550 | 0.72 | L3MBTL1 (0.44) | CYP3A4CYP2D6POLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029090-A1 | CHEMICAL PROCESS | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | WO | disclosed |